Kavinace Ultra PM

Kavinace Ultra PM is uniquely designed to promote sleep by promoting healthy levels of the primary neurotransmitters and hormones involved in sleep. It is frequently recommended for patients with elevated levels of glutamate and PEA, decreased levels of serotonin and melatonin, and may be beneficial in some individuals with elevated epinephrine and norepinephrine.

• 4-amino-3-phenylbutyric acid crosses the blood brain barrier and binds GABA-B receptors*1
• GABA is associated with mood and anxiousness2
• 5-HTP is a precursor to serotonin*3
• Serotonin is associated with mood and sleep4
• Melatonin is important for the regulation of the sleep-wake cycle*5

References

1. Lapin 2001.
2. Kalueff and Allan 2007.
3. Li et al. 2013.
4. Ursin 2002; Dell-Osso et al. 2016.
5. Brown 1994.