Immune Maintenance

Foundational immune support formula featuring synergistic nutrients and botanicals that promote healthy immune function

• Provides comprehensive immune defense
• Enhances overall immune health
• Supports innate and adaptive immune response

Patient One Immune Maintenance is a comprehensive formula that nutritionally supports immune health by strengthening the bodys natural defenses. It provides a complementary combination of vitamins, trace minerals and proven botanicals that provide a foundation for overall wellness and enhanced immune system function.

Immune Maintenance supplies Vitamin C, Vitamin D3, Zinc (as TRAACS® glycinate chelate) and Citrus Bioflavonoids, along with Arabinogalactan and Reishi mushroom. Astragalus is included for additional immune support and its adaptogenic actions in helping to protect against the effects of occasional stress.

Immune Maintenance may be used year-round or at times when the immune system is challenged by environmental stressors.

Key Ingredients

Immune Supportive Vitamins and Minerals
Nutrients including vitamin C, vitamin D and zinc work synergistically to support healthy immune cell production and activity.

Vitamin C has been widely studied and is commonly known for its role in moderating the severity or duration of acute immune challenges. It appears to heighten the immune response to infections, impacting T-cell proliferation. This nutrient also plays a role in the deactivation of histamine.

Vitamin D can modulate the innate and adaptive immune responses. Deficiency in vitamin D is associated with increased autoimmunity as well as an increased susceptibility to infection. Vitamin D stimulates the production of cathelicidin, a protein with natural antibiotic properties.

The essential trace mineral zinc is involved in nearly every aspect of the immune system’s function. The body requires zinc to develop and activate T-lymphocytes. Even mild to moderate degrees of zinc deficiency can impair macrophage and neutrophil functions and natural killer cell activity. Researchers have hypothesized that zinc could reduce the severity and duration of cold symptoms by directly inhibiting rhinovirus binding and replication in the nasal mucosa and suppressing inflammation. Low zinc status has been associated with increased susceptibility to pneumonia and other infections in children in developing countries and the elderly. Zinc in Immune Maintenance is supplied as TRAACs®, a patented mineral amino acid chelate shown to have superior absorption.

Citrus Bioflavonoids
Our formula includes citrus bioflavonoids, phytonutrients found in plants such as vitamin C-rich citrus fruit that are vital for proper absorption of vitamin C. Studies have shown their ability to enhance and prolong the action of vitamin C. Like vitamin C, bioflavonoids also support healthy histamine release.

Astragalus
A well-known Chinese herb, Astragulus stimulates white blood cells to both prevent and fight infections. Classified as an adaptogen, this botanical helps protect the body against various stresses, including physical, mental, or emotional stress. Astragalus has antibacterial and anti-inflammatory properties. Studies have shown that astragalus has antiviral properties and stimulates the immune system, suggesting that it may help protect against colds.

Arabinogalactan and Reishi Mushroom
Beta glucans are polysaccaride compounds that play an instrumental role in nutritionally supporting the immune system. Beta glucans support the macrophages and the immune cascade, an innate physiological immune response. In this formula, polysaccharides from arabinogalactan and reishi mushroom provide complementary support for immune cell function and healthy immune mediator activity.

Arabinogalactan, a fermentable fiber found in high concentrations in North American larch trees, has demonstrated the ability to activate immune cells involved with the body’s first line of defense. It promotes cytokine production, the communication and signaling compounds of immune cells. It has also demonstrated the ability to promote the growth of beneficial bacteria. The vitamin C in Immune Maintenance may enhance arabinogalactan activity.

Mushrooms and humans share common microbial antagonists, including Escherischia coli, Staphylococcus aureus, and Pseudomonas aeruginosa, against which the fungi have developed potent chemical defenses. Reishi (Ganoderma lucidum) is a valuable medicinal mushroom for immune system enhancement. Reishis Beta-D-glucan assists macrophage maturation. Reishi also has a triterpene compound that is believed to be a generalized immunomodulator and anti-allergen. Reishi activates macrophages and T-lymphocytes, enhancing cytokine levels.

Research

• A double-blind, randomized, placebo-controlled clinical trial with 48 men and women was conducted to investigate the efficacy and safety of Astragalus membranaceous in the treatment of patients with seasonal allergic rhinitis. The study revealed a significant number of positive signals indicating the therapeutic effectiveness.
• In vitro and in vivo studies suggest some immune stimulating effects of astragalus. It has shown in vitro antibacterial activity against Shigella dysenteriae, Streptococcus hemolytic, Diplococcus pneumonia, and Staphylococcus aureus.

References

1. Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceous in the treatment of patients with seasonal allergic rhinitis. Phytother Res. 2010;24:175-81.
2. Shao BM, Xu W, Dai H, et al. A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceous, a Chinese medicinal herb. Biochem Biophys Res Commun. 2004;320(4):1103-1111.
3. Mao SP, Cheng KL, Zhou YF. [Modulatory effect of Astragalus membranaceous on Th1/Th2 cytokine in patients with herpes simplex keratitis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004;24(2):121-123.
4. English HN, Hay S, Macfarlane GT. Polysaccharide breakdown by mixed populations of human faecal bacteria. FEMS Microbiology Ecology 1987;95:163-171.
5. Causey JL, Robinson RR, Feirtag JM, et al. Effects of larch arabinogalactan on human peripheral blood mononuclear cells: results from in vivo and in vitro human trials. Unpublished results.
6. Egert D, Beuscher N. Studies on antigen specificity of immunoreactive arabinogalactan proteins extracted from Baptista tinctorial and Echinacea purpurea. Plants Med 1992;58:163-165.
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