Riboflavin 5 Phosphate

Thorne Research


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The bioactive, tissue ready form of riboflavin*

  • the active form of vitamin B2 more readily used by the body*
  • important cofactor for formation of other B vitamins, including niacin and active B6
  • necessary for methylation pathways in the body*
  • not derived from yeast

Riboflavin, also known as vitamin B2, plays a key role in the activation and conversion of other B vitamins.* For instance, it is necessary for activation of vitamin B6, conversion of tryptophan to niacin, and conversion of folate to its various active forms.* Riboflavin also plays a crucial role in fat and glucose metabolism, red blood cell synthesis, and the production and regulation of certain hormones.*

As with many B vitamins, riboflavin must be converted to its active form – riboflavin 5-phospate (R5P) – in order for it to be utilized by the body. Because absorption of riboflavin occurs in the upper GI tract, a compromised digestive system can adversely affect the bodys ability to convert riboflavin to R5P.* In addition, certain prescription medications can interfere with the proper absorption of riboflavin and deplete the body of its stores.