Triple Action Cruciferous Vegetable Extract

Life Extension

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Scientists have identified specific extracts from cruciferous vegetables — such as broccoli, cauliflower, cabbage and Brussels sprouts — that help maintain healthy hormone levels.1-11 Maintaining optimal hormone balance is essential to any anti-aging strategy. Triple Action Cruciferous Vegetable Extract combines some of these botanical extracts into the most comprehensive food-based, plant compilation for cell protection yet.

I3C (Indole-3-carbinol) and DIM (Di-indolyl-methane) favorably modulate estrogen metabolism and induce liver detoxification enzymes to help neutralize potentially harmful estrogen metabolites and xenoestrogens (estrogen-like environmental chemicals).12-16

Extracts of broccoli, watercress, and rosemary provide glucosinolates, isothiocyanates, carnosic acid, and carnosol — bioactive compounds that have a multitude of favorable effects on estrogen metabolism and cell division.17-20 Apigenin, a powerful plant flavonoid, is also added to the formula to boost cell protection, 21 while cabbage extract, a natural source of benzyl isothiocyanate (BITC), is included to maintain cell health.8, 22

Life Extension has combined its cruciferous vegetable complex with trans-resveratrol based on indications from published scientific literature that resveratrol may be the most effective compound for maintaining optimal health and promoting longevity.23 The whole grape extract contains a spectrum of polyphenols naturally found in red wine, such as proanthocyanidins, anthocyanins, and flavonoids.

References

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  8. PLoS One. 2012;7(2):e32267.
  9. Mol Cell Endocrinol. 2012 Nov 5;363(1-2):74-84.
  10. Breast. 2012 Aug 6. [Epub ahead of print]
  11. Biopharm Drug Dispos. 2012 Nov 8. doi: 10.1002/bdd.1826. [Epub ahead of print]
  12. Biochem Pharm. 2002, 64;393-404. 
  13. Toxicol Appl Pharm. 2001 Jul 15;174(2):146-52. 
  14. In Vivo. 2006 Mar-Apr;20(2):221-8. 
  15. Cancer Detect Prevent. 2004;28:72-9.
  16. Mol Carcinog. 2012 Mar;51(3):244-56.
  17. Carcinogenesis. 2002 Apr;23(4):581-6. 
  18. Mol Cancer Ther. 2003 Oct;2(10):1045-52. 
  19. Biosci Biotechnol Biochem. 2012;76(1):115-9. 
  20. J Complement Integr Med. 2012 Jul 2;9(1):Article13.doi:10.1515/1553-3840.1611.
  21. J Clin Biochem Nutr.2009 May;44(3):260-5. 
  22. Food Chem Toxicol. 2008 Jul;46(7):2358-64. 
  23. ClinIntervAging. 2008;3(2):331-9.